Selfish sperm see older fathers pass on more disease-causing mutations | New Scientist
Research shows that men who father children at an older age may pass on more harmful genetic mutations due to changes in sperm cells over time. Scientists have found that some sperm can act “selfishly,” favoring their own survival and replication, which increases the likelihood of mutations linked to various diseases. These mutations are particularly associated with conditions such as autism, schizophrenia, and developmental disorders. The study highlights how the aging process in men affects reproductive cells at the genetic level, offering new insights into inheritance and disease risk. Understanding this mechanism could guide family planning decisions and inform medical research into genetic conditions. While older fathers are not guaranteed to pass on harmful mutations, the probability rises with age, emphasizing the importance of awareness around paternal age and reproductive health.
The Key points
- Older men may transmit more harmful genetic mutations.
- Certain sperm act “selfishly,” increasing mutation rates.
- Mutations are linked to autism and schizophrenia.
- Paternal age directly influences sperm genetic changes.
- Disease-causing mutations accumulate as men age.
- Study provides insight into inheritance patterns.
- Sperm behavior affects mutation propagation.
- Genetic risks are higher with delayed fatherhood.
- Research aids understanding of reproductive genetics.
- Awareness of paternal age can guide family planning.
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